Idiopathic Hypoparathyroidism Presenting as Adult Onset Seizures

Abstrakt

Idiopathic hypoparathyroidism is a rare disorder of unknown etiology. It usually presents by second decade of life but delayed manifestations are known to occur. It presents as neuromuscular excitability, numbness, carpopedal spasm, 1 cramps, laryngeal stridor and convulsions. In subtle cases of hypoparathroidism neuromuscular excitability can be made evident by eliciting Chovstek's and Trousseu's 2 sign. Typical ECG manifestations are QTC prolongation. Cataract, intracranial calcification are well known entities. 3 Various other manifestations are Parkinsonism, Choreo athetosis, Spasm etc. Typically patients have low serum calcium, high inorganic phosphorus with low to undetectable PTH. In all such patients renal failure, chronic GI disorders, persistent alkalosis, rickets and osteomalacia should be excluded. JMS 2012;15(2):182-83